Infrapatellar Fat Pad and Knee Osteoarthritis

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چکیده

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An emerging player in knee osteoarthritis: the infrapatellar fat pad

The role of inflammation in the development, progression, and clinical features of osteoarthritis has become an area of intense research in recent years. This led to the recognition of synovitis as an important source of inflammation in the joint and indicated that synovitis is intimately associated with pain and osteoarthritis progression. In this review, we discuss another emerging source of ...

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Infrapatellar fat pad in the knee: is local fat good or bad for knee osteoarthritis?

INTRODUCTION Recent studies regarding the infrapatellar fat pad (IPFP) mainly focus on the roles of the cells derived from the IPFP. There have been few clinical or epidemiological studies reporting on the association between the IPFP and knee osteoarthritis (OA). Our objective is to generate hypotheses regarding the associations between IPFP maximum area and knee OA measures in older adults. ...

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Expression of calcitonin gene-related peptide in the infrapatellar fat pad in knee osteoarthritis patients

BACKGROUND The infrapatellar fat pad (IPFP) has been implicated as a possible source of osteoarthritis (OA) development and knee pain due to the production of inflammatory mediators and the existence of nerve fibers within this structure. Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that is localized to joint tissues and has recently been implicated in the development o...

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A Case of Infrapatellar Fat Pad Ganglion of the Knee

Introduction A ganglion cyst can induce symptoms around the knee and should be considered as an intra-articular mass in differential diagnosis. Case Presentation A 22-year-old female presented with a persistent medial knee joint pain in her left knee for 2 years. There was soft tissue swelling on the anteromedial aspect of the infrapatellar region on her left knee. Lachman and McMurray tests ...

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Infrapatellar fat pad-derived mesenchymal stem cell therapy for knee osteoarthritis.

PURPOSE The aim of the study was to determine if isolated mesenchymal stem cells (MSCs) derived from the infrapatellar fat pad could effectively improve clinical results when percutaneously injected into arthritic knees. LEVEL OF EVIDENCE Therapeutic case-control study; Level III. METHODS Twenty five stem cell injections combined with arthroscopic debridement were administered to patients w...

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ژورنال

عنوان ژورنال: Aging and disease

سال: 2020

ISSN: 2152-5250

DOI: 10.14336/ad.2019.1116